iClusterPlus is developed for integrative clustering analysis of multi-type genomic data and is an enhanced version of iCluster proposed and developed by Shen, Olshen and Ladanyi (2009). Multi-type genomic data arise from the experiments where biological samples (e.g. tumor samples) are analyzed by multiple techniques, for instance, array comparative genomic hybridization (aCGH), gene expression microarray, RNA-seq and DNA-seq, and so on. In the iClusterPlus model, binary observations such as somatic mutation are modeled as Binomial processes; categorical observations such as copy number states are realizations of Multinomial random variables; counts are modeled as Poisson random processes; and continuous measures are modeled by Gaussian distributions.

","plain":"iClusterPlus is developed for integrative clustering analysis of\nmulti-type genomic data and is an enhanced version of iCluster proposed\nand developed by Shen, Olshen and Ladanyi (2009). Multi-type genomic\ndata arise from the experiments where biological samples (e.g. tumor\nsamples) are analyzed by multiple techniques, for instance, \"array\ncomparative genomic hybridization\" (aCGH), gene expression microarray,\nRNA-seq and DNA-seq, and so on. In the iClusterPlus model, binary\nobservations such as somatic mutation are modeled as Binomial processes;\ncategorical observations such as copy number states are realizations of\nMultinomial random variables; counts are modeled as Poisson random\nprocesses; and continuous measures are modeled by Gaussian\ndistributions.\n\n","locale":"en_US.UTF-8"},"home-page":"https://bioconductor.org/packages/iClusterPlus/","derivations":[{"system":"x86_64-linux","target":"","derivation":"/gnu/store/almcpkkaa6gsqmdybynrfrq71vv7avsl-r-iclusterplus-1.26.0.drv"},{"system":"powerpc64le-linux","target":"","derivation":"/gnu/store/2kl5qf8rk0mqjrnybwfl6qaik76p9w8k-r-iclusterplus-1.26.0.drv"},{"system":"mips64el-linux","target":"","derivation":"/gnu/store/h1xqnjybjp83rzsp3735wn4714qajiyf-r-iclusterplus-1.26.0.drv"},{"system":"i686-linux","target":"","derivation":"/gnu/store/rvx6f6gli3d3sf2nvk685azhnxrxkqdc-r-iclusterplus-1.26.0.drv"},{"system":"i586-gnu","target":"","derivation":"/gnu/store/gwrhvdn3q49c3ivndrvzds01hwsxbghf-r-iclusterplus-1.26.0.drv"},{"system":"armhf-linux","target":"","derivation":"/gnu/store/ix9y0cadqygqdfx03vqi7q9z0c19wk0d-r-iclusterplus-1.26.0.drv"},{"system":"aarch64-linux","target":"","derivation":"/gnu/store/8b5n538wfskk5lp65l91wsgyxad7ry2d-r-iclusterplus-1.26.0.drv"}]}